Large cell acanthoma: a debate throughout the decades

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Large cell acanthoma: a debate throughout the decades

Commentary | Dermatol Pract Concept 2013;4(1):5 43 Have we really concluded what a large cell acanthoma is? Is it a distinct entity, a solar lentigo, a subtype of seborrheic keratosis, or an HPV-induced acanthoma? In 1970, large cell acanthoma (LCA) was first described by Pinkus, as a sharply demarcated, hyperkeratotic patch, often on sun-exposed skin, characterized by extraordinarily large cel...

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Reflectance confocal microscopy (RCM) is an FDA approved noninvasive optical imaging technique that acquires cellular level-resolution skin images in vivo. Herein, we report a case of histopathologically proven large cell acanthoma (LCA) whose RCM features simulate those of squamous cell carcinoma in situ.

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ژورنال

عنوان ژورنال: Dermatology Practical & Conceptual

سال: 2014

ISSN: 2160-9381

DOI: 10.5826/dpc.0401a05